Advanced - For experienced high school and college classes; requires some technical skill.

• Simple microarray simulation
• No special equipment
• Comprehensive 2-to-4 day lesson plan
• 45-minute experiment
• Affordable lab option

This microarray simulation provides an inexpensive, hands-on lab to introduce students to microarrays, the complexities of gene expression, and the role of gene expression in cancer. Using simulated microarray technology, students compare the relative expression levels of 6 different genes in healthy lung cells and lung cancer cells.

Students then discuss the significance of the relative expression levels with respect to the genes' roles in causing cancer. Teacher's manual includes instructions for a bonus dry lab.

Lab Kit includes:

• Glass Slides
• Simulated Hybridization Solution
• 6 Simulated cDNA Solutions
• Instructions with Student Masters
• Pack of 30 Student Worksheets

"We ran this simulation in a 300-level Genetics lab (college not high school) last semester along with the supplementary math analysis that Dr. Laurie Heyer and Dr. Malcolm Campbell (Davidson College) developed. It was a great success! Not only did the students enjoy the lab,... they [also] had significant gains in understanding. I really like this simulation!" -- Pamela A. Marshall, Ph.D., Assistant Professor of Integrated Natural Sciences - Arizona State University at the West campus