Students can perform 21 double-replacement reactions in a microplate and compare the results with their predictions. In addition, students determine the identities of 2 unknown solutions. In the second part of the experiment students synthesize an amphoteric substance and study its reaction chemistry by treating the compound with water, acid, and base. This laboratory exercise provides valuable experience in writing and balancing molecular, ionic, and net ionic equations. Materials are sufficient for 30 students working in pairs. Materials needed, but not supplied, include fifteen 24-well microplates (item# 840723, pack of 12).