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Sickle-Cell Anemia Protein Electrophoresis 4-Station Kit (with prepaid coupon)

Item # 211031 Exclusive

Sickle-cell anemia is a classic classroom example of the overarching impact of a single point mutation in the human genetic code. The activity allows your students to further explore this human disease while they learn about protein structure, genetic inheritance, and human evolution. Because the lab requires no additional staining time and uses recombinant hemoglobin samples, it is one of the fastest, safest, and most realistic ways to bring protein electrophoresis into your classroom.

This item has been discontinued.

Intermediate—Easy to perform; requires some background knowledge.

  • Explore the role of protein structure and genetics in human disease
  • Designed for the classroom: no gel staining required
  • Uses recombinant hemoglobin samples to provide true-to-life results without any pathogen risk

Need a new way to help students make connections between the impact of mutations on protein structure? Or looking for labs that make real-world disease connections and link to larger concepts such as evolution? Either way, the Sickle-Cell Anemia Protein Electrophoresis Kit is perfect for your biology classroom. Students work with real-world samples, recombinant hemoglobin (poses zero pathogen risk), to conduct a genetic screen on a family and make determinations about the family’s disease state. As a bonus, the kit works on agarose gels and does not require in-class staining, saving you money and time over typical protein electrophoresis kits. This 4-Station Kit is designed for students working in groups of 2 to 4. Note: Kit includes a prepaid coupon to request the perishables later at your convenience. Contact us or return the coupon to request delivery of perishable materials.

   This item is sold and shipped to schools and businesses only. Not available to individuals or residential addresses. For substitution suggestions, please call us at 800.334.5551 (8am to 8pm, ET, Monday-Friday).

  • This item is only available from Carolina Biological Supply Company.
  • This item is sold and shipped to schools and businesses only. Not available to individuals or residential addresses. Visit our Login & Registration page to learn how to create a Login and link it to an approved school or business account.

This item includes a prepaid coupon for living or perishable materials (all items). Redeem the coupon for delivery of these materials at your convenience at www.carolina.com/livingform, by phone at 800.334.5551, or by fax at 800.222.7112.

Components Qty Included?
Hemoglobin A Control, Tube 4 Included
Hemoglobin S Control, Tube 4 Included
Hemoglobin Maternal Sample, Tube 4 Included
Hemoglobin Paternal Sample, Tube 4 Included
Hemoglobin Twin 1 Sample, Tube 4 Included
Hemoglobin Twin 2 Sample, Tube 4 Included
5x Protein Loading Dye, 600 µL 1 Included
Fine Sieving Agarose, 5 g 1 Included
5x Tris-Glycine Buffer, 600 mL 1 Included
Teacher’s Manual with Reproducible Student Guide 1 Included
Containers of Crushed Ice 4 Needed, Not Included
Electrophoresis Chambers with Gel Trays 4 Needed, Not Included
Flask, 1 L 1 Needed, Not Included
Distilled or Deionized Water, 3.5 L 1 Needed, Not Included
Microcentrifuge Tubes 3 Needed, Not Included
Flask, 3 L 1 Needed, Not Included
Electrophoresis Power Supplies 2 Needed, Not Included
Micropipettes and Tips Needed, Not Included
Graduated Cylinder, 2 L Needed, Not Included
Hot Plate, Microwave, or Water Bath Needed, Not Included
White Light Box Needed, Not Included
Heat-Resistant Gloves Needed, Not Included
Aluminum Foil or Parafilm® Needed, Not Included
Microcentrifuge (optional) Needed, Not Included
Camera (optional) Needed, Not Included
Carolina Biological Supply

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2700 York Road, Burlington, NC 27215-3398 • 800.334.5551