We use cookies to provide you with a great user experience. By using our site, you accept our use of cookies. You can review our cookie and privacy policy here.
  • Service & Support

    Contact Us

    Our Customer Service team is available from 8am to 6:30pm, ET, Monday through Friday. Live chat is available from 8am to 5:30pm ET, Monday-Friday.

    Call:
    800.334.5551
    Fax:
    800.222.7112
    Email:
    Email Customer Service
    Chat:
    Live Chat
     

    International Sales & Service

    We serve educators in more than 170 countries worldwide. Create a quote request on our website or contact our International Sales Team.

    International Ordering
  • Shopping
    Lists

    Login or register now to maximize your savings and access profile information, order history, tracking, shopping lists, and more.

  • Quick
    Order
  • My Cart
    0

    My Cart

    Your Shopping Cart is currently empty. Use Quick Order or Search to quickly add items to your order!

Antibody and Antigen Models Set

$69.00
(ships from manufacturer, est arrival 10/24/22)

Description

Use these 3-dimensional antibody and antigen models to introduce your students to the protein structure of the antibody—composed of 12 repeating immunoglobulin folds—before discussing its role in the immune system.

Antibodies are an important protein of the immune system; they recognize and bind to antigens, triggering a variety of immune responses that protect the cell from infection. Modular in design, they are composed of 2 heavy chains and 2 light chains. Each heavy chain is composed of 4 immunoglobulin folds. Each immunoglobulin fold consists of 2 flat beta sheets held together by a covalent disulfide bond between 2 cysteine amino acids, found in one of the beta sheets. Each light chain consists of 2 immunoglobulin folds. The antigen binding site is located at the ends of these Y-shaped proteins, where immunoglobulin folds from each chain come together.

Antibodies are difficult to study because they are so flexible. However, in the 1960s, Rodney Porter and Gerald Edelman independently determined the structure of the antibody using different techniques. They shared the 1972 Nobel Prize in Physiology or Medicine for their work.

On the plastic 8-1/2" antibody model, the heavy chains are yellow, the light chains are red, and the carbohydrate is blue, which stabilizes the heavy chains in the molecule. On the nylon 3-1/2" antigen model, the heavy chains are white, the light chains are red, and the carbohydrate is blue. Models should be handled with care.

These models can be used in conjunction with the Flu Fight: Immunity & Infection© Panorama Cellular Landscape Poster (item #211158, sold separately) to actively simulate antibody binding and specificity.

Specifications

What’s Included:
  • 1 Antibody Model
  • 2 Antigen Model
Return Policy:

If for any reason you are not satisfied with this item, it is eligible for a return, exchange, refund, or credit up to 180 days from date of purchase. Restrictions may apply. Returns & Exchanges Policy.

Reviews

Questions & Answers

Loading...