3-D Learning
Molecules to Organisms
Structure & Function
$103.95
Engineer a physical model of a circulatory system with a 2-chambered heart and blood vessels throughout a body.
PE: HS-LS1-2 Related PE: HS-ETSI-2
Time Requirement: 3 45-minute Class Periods
SEP: Developing and using models CCC: Systems and system models
DCI: LS1.A: Structure and Function
$69.95
Use a simple purification process to isolate green fluorescent protein while developing a model for how genetic engineering is used to make recombinant proteins.
PE: HS-LS1-1 Related PE: HS-LS1-3
Time Requirement: 3 45-minute Class Periods
SEP: Developing and using models CCC: Structure and function
DCI: LS1.A: Structure and Function
$49.95
Investigate human subject heart rates, before and after exercise, and Daphnia heart rates, after applying acetylcholine, to provide evidence of feedback mechanisms.
PE: HS-LS1-3 Related PE: HS-LS1-2
Time Requirement: 3 45-minute Class Periods
SEP: Planning and carrying out investigations CCC: Stability and change
DCI: LS1.A: Structure and Function
$238.00
Develop and revise a model for relationships between organ systems through an authentic forensic dissection protocol used on a preserved pig.
PE: HS-LS1-2 Related PE: HS-LS1-4
Time Requirement: 4 45-minute Class Periods
SEP: Developing and using models CCC: Structure and function
DCI: LS1.A: Structure and Function

Modeling DNA to Protein
COMING SOON
Using manipulatives, model the flow of information through DNA translation and transcription of a region on the beta-hemoglobin gene, then apply the model to the mutation associated with sickle-cell disease and its physiological effects.
PE: HS-LS1-1 Related PE: HS-LS3-2
Time Requirement: 2 45-minute Class Periods
SEP: Developing and using models, Obtaining, evaluation, and communicating information CCC: Patterns
DCI: LS1.A: Structure and Function
Growth & Development
$203.50
Use a model to simulate mitosis, meiosis, and crossing-over in animal cells.
PE: HS-LS1-4 Related PE: HS-LS3-1
Time Requirement: 3 45-minute Class Periods
SEP: Engaging in argument from evidence CCC: Cause and effect: Mechanism and expanation
DCI: LS3.B: Variation of Traits
$69.95
Investigate tissue regeneration in planaria to build a predictive model for regeneration patterns based on stem cell locations.
PE: HS-LS1-4 Related PE: HS-LS1-2
Time Requirement: 4 45-minute Class Periods
SEP: Planning and carrying out investigations CCC: Patterns
DCI: LS1.B: Growth and Development
Matter & Energy Flow
$99.95
Produce a refined model of photosynthesis that includes the role light wavelengths play in the photosynthesis process.
PE: HS-LS1-5 Related PE: HS-LS2-5
Time Requirement: 2 45-minute Class Periods
SEP: Developing and using models CCC: Energy and matter: Flows, cycles, and conservation
DCI: LS1.C: Matter and Energy Flow
$89.95
Identify large hydrocarbons from food nutrient tests and design an experiment to identify nutrient hydrocarbons in unknown samples.
PE: HS-LS1-6 Related PE: HS-LS1-7
Time Requirement: 2 45-minute Class Periods
SEP: Planning and carrying out investigations CCC: Structure and function
DCI: LS1.C: Matter and Energy Flow

Carolina BioKits®: Investigating Cellular Respiration with Yeast Beads
COMING SOON
Use experimental evidence to argue that yeast can perform cellular respiration in the presence or absence of oxygen in a system.
PE: HS-LS1-7 Related PE: HS-LS2-3
Time Requirement: 2 45-minute Class Periods
SEP: CCC:
DCI: LS1.C: Matter and Energy Flow
$76.55
Refine the design of an apparatus that uses enzymes and microbes to produce ethanol.
PE: HS-LS2-3 Related PE: HS-ETS1-1
Time Requirement: 3 45-minute Class Periods
SEP: Constructing explanations and designing solutions CCC:
DCI: ETS1.A: Defining and Delimiting Engineering Problems
Ecosystems
Interdependent Relationships
$89.95
Conduct an investigation to gather evidence and make a claim regarding taxonomic diversity of protists at different temperatures.
PE: HS-LS2-2 Related PE: HS-LS4-6
Time Requirement: 3 45-minute Class Periods
SEP: Engaging in argument from evidence CCC: Stability and change
DCI: LS2.C: Ecosystem Dynamics

Carrying Capacity and Algal Blooms
COMING SOON
Analyze patterns in sample populations to determine conditions that influence algal growth rate, and then relate these factors to the ecological phenomenon of algal blooms, carrying capacity, and eutrophication.
PE: HS-LS2-1 Related PE: HS-LS2-7
Time Requirement: 4 45-minute Class Periods
SEP: Engaging in argument from evidence CCC:
DCI:
Matter & Energy Cycles
$115.95
Create and refine a small-scale model of the carbon cycle in a closed freshwater system by collecting evidence about plants and animals and their interactions, in daylight and dark environments.
PE: HS-LS2-5 Related PE: HS-LS2-3
Time Requirement: 3 45-minute Class Periods
SEP: Developing and using models CCC: Systems and system models
DCI: LS2.B: Matter and Energy Cycles
$84.75
Construct a model food chain for a system of microorganisms and develop a mathematical model for energy transfer between trophic levels.
PE: HS-LS2-4 Related PE: HS-LS2-5
Time Requirement: 2 45-minute Class Periods
SEP: Using mathematics and computational thinking CCC: Energy and matter: Flows, cycles, and conservation
DCI: LS2.B: Matter and Energy Cycles
Ecosystem Dynamics
$94.95
Through a simulation card game, develop a model of an unstable ecosystem using evidence of population changes due to habitat changes in a temperate forest.
PE: HS-LS2-6 Related PE: HS-LS2-7
Time Requirement: 3 45-minute Class Periods
SEP: Developing and using models CCC: Stability and change
DCI: LS2.C: Ecosystem Dynamics

Succession in a Hay Infusion
COMING SOON
Gather evidence, over time, to argue patterns in the relationships among populations within a hay infusion
PE: HS-LS2-6 Related PE: HS-LS2-1
Time Requirement: 2 45-minute Class Periods
SEP: Planning and carrying out investigations CCC:
DCI:
$77.20
Use a small-scale simulation to collect evidence that microorganisms can be used in the bioremediation of oil spills.
PE: HS-LS4-6 Related PE: HS-LS2-7
Time Requirement: 3 45-minute Class Periods
SEP: CCC:
DCI:
$124.45
After collecting various water samples, use sterile technique to identify and differentiate Escherichia coli from other coliforms, then propose design solutions that reduce the environmental impact of human activities.
PE: HS-LS2-7 Related PE: HS-LS4-6
Time Requirement: 2 45-minute Class Periods
SEP: Constructing explanations and designing solutions CCC: Cause and effect: Mechanism and explanation
DCI: LS2.C: Ecosystem Dynamics
Social Interaction & Group Behavior
$99.95
Evaluate evidence from different insect species that communication and cooperative behaviors can increase the chances of survival.
PE: HS-LS2-8 Related PE: HS-LS4-3
Time Requirement: 4 45-minute Class Periods
SEP: Engaging in argument from evidence, Planning and carrying out investigations CCC: Stability and change
DCI: LS2.D: Social Interactions & Group Behavior
Heredity
Inheritance of Traits

Exploring Electrophoresis Using DNA Evidence
COMING SOON
Use evidence found in DNA fingerprint patterns to argue which suspect committed a crime.
PE: HS-LS3-1 Related PE: HS-LS3-2
Time Requirement: 2 45-minute Class Periods
SEP: Engaging in argument from evidence CCC: Cause and effect: Mechanism and explanation
DCI: LS3.B: Variation of Traits
Variation of Traits
$106.95
After investigating the effect ultraviolet light has on different strains of yeast cells, students design an experiment to test the effectiveness of different ultraviolet preventatives.
PE: HS-LS3-2 Related PE: HS-LS4-2
Time Requirement: 3 45-minute Class Periods
SEP: Asking questions and defining problems CCC:
DCI:
$79.95
Use statistics to verify the results of crosses between 4 different stocks and develop an explanation for the inheritance patterns observed.
PE: HS-LS3-3 Related PE: HS-LS3-2
Time Requirement: 2 45-minute Class Periods
SEP: Analyzing and interpreting data CCC: Cause and effect: Mechanism and explanation
DCI: LS3.B: Variation of Traits
Evolution
Evidence of Common Ancestry
$146.00
Use model DNA nucleotides to complete a DNA analysis for the purposes of establishing a common ancestry and DNA kinship patterns.
PE: HS-LS4-1 Related PE: HS-LS1-1
Time Requirement: 2 45-minute Class Periods
SEP: Developing and using models, Obtaining, evaluating, and communicating information CCC: Patterns
DCI: LS4.A: Evidence of Common Ancestry

Carolina BioKits®: Cladograms and Evolution
COMING SOON
Use external features and DNA evidence to argue evolutionary relationships among a set of organisms.
PE: HS-LS4-1 Related PE: HS-LS1-2
Time Requirement: 3 45-minute Class Periods
SEP: Planning and carrying out investigations CCC:
DCI:
Natural Selection
$118.50
Using 2 strains of Escherichia coli, one sensitive to antibiotics and the other antibiotic resistant, perform experiments to develop a model of the real-time evolution of antibiotic resistant E. coli.
PE: HS-LS4-2 Related PE: HS-LS4-3
Time Requirement: 3 45-minute Class Periods
SEP: Engaging in argument from evidence CCC: Cause and effect: Mechanism and explanation
DCI: LS4.B: Natural Selection
$75.00
Use a simulation of moth populations and environmental changes to develop the concept of genetic equilibrium, then confirm or reject it through allele frequency calculations.
PE: HS-LS4-3 Related PE: HS-LS3-3
Time Requirement: 2 45-minute Class Periods
SEP: Asking questions and defining problems and defining problems CCC:
DCI:
Adaptation and Biodiversity
$107.00
Use evidence gathered from observations of a fruit fly population over time to argue the occurrence of natural selection.
PE: HS-LS4-2 Related PE: HS-LS3-3
Time Requirement: 3 45-minute Class Periods
SEP: Analyzing and interpreting data CCC:
DCI: LS4.B: Natural Selection
$152.75
Gather laboratory evidence of bacterial antibiotic sensitivity and construct an explanation for how antibiotic resistant bacteria evolve.
PE: HS-LS4-4 Related PE: HS-LS4-5
Time Requirement: 3 45-minute Class Periods
SEP: Constructing explanations and designing solutions CCC: Cause and effect: Mechanism and explanation
DCI: LS4.C: Adaptation
$78.95
Use evidence to support claims for how changes in environmental conditions may result in the extinction of a species.
PE: HS-LS4-5 Related PE: HS-LS2-7
Time Requirement: 2 45-minute Class Periods
SEP: CCC:
DCI: