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Description
Students receive a 24-member family tree and DNA samples presumably taken from each family member. They cut the DNA samples with a restriction enzyme and separate the fragments by gel electrophoresis. The genotypes revealed by the class are used to determine the pattern of inheritance of the "gene" being analyzed and to predict each person's phenotype. Kit contains instructions, sets of apparatus, and enough materials to run 5 gels.
Product Details
Intermediate—Easy to perform; requires some background knowledge.
Students receive a 24-member family tree and DNA samples presumably taken from each family member. They determine the genotype of each of the relatives by cutting the DNA samples with a restriction enzyme and separating the fragments by gel electrophoresis. The genotypes revealed by the class are used to determine the pattern of inheritance of the "gene" being analyzed and to predict each person's phenotype. In this simulation, the teacher and students choose a fictitious phenotype to link to the gene, although the principles and issues raised would apply to real situations.
This lab is designed to help your students understand:
- Genetic screening of an extended family
- Classical Mendelian genetics
- Modern molecular biology
- Molecular basis of heredity
- Ethical and social implications of genetic testing
Product Features
- Comes with instructions, sets of apparatus, and enough materials to run 5 gels
- Includes a voucher to request delivery of the perishable materials later at your convenience
If you already have gel electrophoresis apparatus, order just the refill kit (item #211018A or item #211018AP), which contains only the reagents needed to perform this lab.
Note: Kit includes a voucher to request perishable materials later at your convenience. Contact Carolina or return the voucher to request delivery of perishables.
