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Students investigate the relationship among a recessive gene (Adh–), its enzyme product (alcohol dehydrogenase, ADH), and the resulting phenotype. ADH-negative mutants cannot break down the ethanol they consume, leading to intoxication and, ultimately, death from alcohol poisoning.
Students make observations over a 24-hr period, requiring them to take flies home overnight. For 8 groups of up to 4 students each; requires 2 to 3 class periods to complete. Flies must be subcultured before beginning the activity. Kit ships with the perishable materials included.
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