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Genetic Kinship: Following the Globin Gene Through Time 1-Station Kit

(in stock)


Use model DNA nucleotides to complete a DNA analysis for the purposes of establishing a common ancestry and DNA kinship patterns.

PE: HS-LS4-1
Related PE: HS-LS1-1
Time Requirement: 2 45-minute Class Periods

SEP: Developing and Using Models; Obtaining, Evaluating, and Communicating Information
CCC: Patterns
DCI: LS4.A: Evidence of Common Ancestry and Diversity

IntermediateEasy to perform; requires some background knowledge.
This kit introduces genetic similarity and variation by evolutionary processes. Students can examine the evolution of the globin gene family with 3 dynamic activities. In the first activity, students use magnetic nucleotide bases to model DNA and RNA structure. They generate a mutation in the sequence and investigate subsequent changes in the amino acid sequence. In the second activity, students focus on gene duplication by making cladograms. In the final activity, students model biotechnology techniques including restriction enzyme digestion, polymerase chain reaction, and gel electrophoresis to diagnose an individual with sickle cell anemia. This 1-Station Kit equips up to 4 students and includes free 1-year access to digital resources that support 3-dimensional instruction.


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