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Sickle-cell anemia is a classic classroom example of the overarching impact of a single point mutation in the human genetic code. The activity allows your students to further explore this human disease while they learn about protein structure, genetic inheritance, and human evolution. Because the lab requires no additional staining time and uses recombinant hemoglobin samples, it is one of the fastest, safest, and most realistic ways to bring protein electrophoresis into your classroom.

Intermediate—Easy to perform; requires some background knowledge.

• Explore the role of protein structure and genetics in human disease
• Designed for the classroom—no gel staining required
• Uses recombinant hemoglobin samples to provide true-to-life results without any pathogen risk

Need a new way to help students make connections between the impact of mutations on protein structure? Or looking for labs that make real-world disease connections and link to larger concepts such as evolution? Either way, the Sickle-Cell Anemia Protein Electrophoresis Kit is perfect for your biology classroom. Students work with real-world samples, recombinant hemoglobin (poses zero pathogen risk), to conduct a genetic screen on a family and make determinations about the family's disease state. As a bonus, the kit works on agarose gels and does not require in-class staining, saving you money and time over typical protein electrophoresis kits. This 8-Station Kit is designed for students working in groups of 2 to 4. Note: Kit includes a voucher to request the perishables later at your convenience. Contact us or return the voucher to request delivery of perishable materials.

   This item is sold and shipped to schools and businesses only. Not available to individuals or residential addresses. For substitution suggestions, please call us at 800.334.5551 (8am to 8pm, ET, Monday-Friday).