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STC-Middle School™, STC3 Edition: Genes and Molecular Machines 5-Class Unit Kit

Item # 513301U5 Exclusive This product is exclusive to Carolina Biological Supply.

Grades 6–8. In 11 lessons, this unit helps students explore the different ways that organisms reproduce and what that means for their genetics. Students learn how traits are passed from one generation to the next as they study zebra fish, plants, protists, and humans. By the end of the unit, students create their own "creatures" with unique characteristics and follow those traits to their offspring to learn about inheritance. For up to 5 classes of 32 students.



This item will ship on or about 8/18/21

Grades 6–8. Unit Driving Question: How has human understanding of inheritance allowed us to influence change in biodiversity?
Unit Highlight—In 11 lessons and beginning at the cellular level, the Genes and Molecular Machines unit helps students explore the different ways that organisms reproduce and what that means for their genetics. Students learn how traits are passed from one generation to the next as they study zebra fish, plants, protists, and humans. By the end of the unit, students create their own "creatures" with unique characteristics and follow those traits to their offspring to learn about inheritance. Using Punnett squares, DNA, and mutations, they predict future generations.

From the STC3 Edition, Genes and Molecular Machines addresses the performance expectations, science and engineering practices, and crosscutting concepts deemed appropriate for grades 6 through 8 by the Next Generation Science Standards* (NGSS). This unit allows students to develop an understanding of phenomena that influence the many different fields of genetics. By completing the unit, students and teachers alike will develop a better understanding of how traits are inherited and how humans have influenced traits in various organisms.

Each lesson in this unit builds on the skills and concepts presented in previous lessons. As students progress through the unit, they take increasing responsibility for their own learning. Eventually, students plan and conduct their own procedures, and they analyze the results obtained. Therefore, the unit should be taught in its entirety; it should not be used as a sourcebook of occasional experiments.

To structure and scaffold the development of students' knowledge, skills, and cognitive reasoning, this unit includes 3 primary lesson types: pre-assessment, skills and knowledge building, and assessment. The pre-assessment lesson allows educators to access students' preconceptions, misconceptions, and skills. The skills and knowledge-building lessons provide multiple opportunities for students to grow and learn through formative assessment. The assessment lesson includes both performance and written assessment activities that function together as a summative assessment of student learning.

This 5-Class Unit Kit comes with a Teacher Edition, teacher access to Carolinascienceonline.com, 16 reusable hardbound Student Guides (item #513303), student eBook access, coupons for prepaid delivery of the living organisms, and the materials needed for a teacher to teach up to 5 classes of 32 students per day. Note: Among the additional materials that will be needed but not supplied in the kit are 16 microscopes (we recommend item #591182).

Next Generation Science Standards*
Performance Expectations

  • MS-LS1-1. Conduct an investigation to provide evidence that living things are made of cells: either one cell or many different numbers and types of cells.
  • MS-LS1-4. Use argument based on empirical evidence and scientific reasoning to support an explanation for how characteristic animal behaviors and specialized plant structures affect the probability of successful reproduction of animals and plants, respectively.
  • MS-LS3-1. Develop and use a model to describe why structural changes to genes (mutations) located on chromosomes may affect proteins and may result in harmful, beneficial, or neutral effects to the structure and function of the organism.
  • MS-LS3-2. Develop and use a model to describe why asexual reproduction results in offspring with identical genetic information and sexual reproduction results in offspring with genetic variation.
  • MS-LS4-4. Construct an explanation based on evidence that describes how genetic variations of traits in a population increase some individuals' probability of surviving and reproducing in a specific environment.
  • MS-LS4-5. Gather and synthesize information about the technologies that have changed the way humans influence the inheritance of desired traits in organisms.
  • MS-LS4-6. Use mathematical representations to support explanations of how natural selection may lead to increases and decreases of specific traits in populations over time.

Disciplinary Core Ideas

  • LS1.A: Structure and function
  • LS1.B: Growth and development of organisms
  • LS3.A: Inheritance of traits
  • LS3.B: Variation of traits
  • LS4.B: Natural selection
  • LS4.C: Adaptation

Science and Engineering Practices

  • Analyzing and interpreting data
  • Engaging in argument from evidence
  • Planning and carrying out investigations
  • Constructing explanations and designing solutions
  • Asking questions and defining problems
  • Obtaining, evaluating, and communicating information
  • Developing and using models

Crosscutting Concepts

  • Cause and effect
  • Scale, proportion, and quantity
  • Patterns
  • Systems and system models
  • Structure and function
  • Interdependence of engineering, technology, and applications of science
  • Science addresses questions about the natural and material world

Lesson Summaries
Lesson 1: Pre-Assessment

Focus Question: What do you already know about cells, reproduction, and genetics?
Students perform short, simple investigations that evaluate their existing knowledge of one or more concepts related to genetics. Students plant Wisconsin Fast Plant® seeds, root a coleus plant, observe variations in zebrafish, examine cells, and look for similarities between parents and offspring. Students are also introduced to model organisms and their significance in life science.
Lesson 2: Cells
Focus Question: What are the building blocks of life?
Students carry out investigations relating to cells by creating wet-mount slides of various organisms that allow them to distinguish between unicellular and multicellular organisms. Next, students analyze prepared slides and attempt to interpret cell function within a multicellular organism. Finally, students consider the function of bones in an animal and design a cell whose structure would adequately meet that function.
Lesson 3: Organism Reproduction
Focus Question: What can cells tell us about how organisms reproduce?
Students cross-pollinate the flowers of their Wisconsin Fast Plants®, simulating sexual reproduction. Students then investigate various asexual methods of reproduction under the microscope by observing paramecium undergoing fission and hydras undergoing budding. Students continue to explore asexual reproduction by regenerating a blackworm segment and analyzing the results of their coleus clipping. Students then consider the advantages and disadvantages of sexual and asexual reproduction and the offspring that are created as a result.
Lesson 4: Cellular Reproduction
Focus Question: Where do cells come from?
Students explore cell division and how it relates to reproduction. Students prepare and stain a wet-mount slide of onion root cells undergoing mitosis. Students then design and construct a model of a cell and predict the behaviors of the cell during mitosis. Next, students explore plant reproductive cells undergoing meiosis. Students use their observations to design and construct a model of a cell and predict the cell behaviors that occur during meiosis. Students compare and contrast these two cellular divisions and how they both relate to reproduction.
Lesson 5: Genetics
Focus Question: Why do family members look similar but not identical to one another?
Students begin to investigate variation by observing a lady beetle population. Students then explore complete dominance by using probability to determine genotypes and phenotypes in a newly created creature. Next, students take those creatures and demonstrate heredity by using a die to randomly pass on genes to an offspring. Students then create Punnett square models that allow them to analyze and interpret the passing of traits from parents to offspring.
Lesson 6: DNA to Trait
Focus Question: How does DNA determine the traits that organisms have?
Students analyze the structure of DNA and determine the patterns that exist in the structure. Students then carry out an investigation to extract DNA from strawberries. Next, students use pop beads to model DNA transcription into RNA, and then translate the RNA into amino acids, forming proteins. Using their creatures from Lesson 5, students then explore how changes in DNA can lead to changes in a protein which leads to changes in the creature's traits.
Lesson 7: Successful Reproduction and Offspring
Focus Question: How do behaviors and structures allow plants and animals to reproduce more successfully and better survive?
Students analyze various flowers and pollinators to determine which pair relies on one another for reproductive success. Then, students plan and carry out an investigation to determine how various seeds are dispersed. Next, students plan and carry out an investigation to explore materials and ideal conditions needed for a seed to germinate. Then, students develop and present a model of a new species of flower, its pollinator, seed structure, and method of dispersal. To end the lesson, students determine the reproductive success of some animals based on parenting strategies.
Lesson 8: Variation
Focus Question: How do differences within a population help a species survive?
Students harvest and germinate the Wisconsin Fast Plant® seeds from their plants. Students then observe the variations that exist between the plants. Next, students use the phenotypes that they observe to predict the genotype of the parents by using Punnett square models. Students then use beads to investigate genetic diversity within asexual and sexual reproducing organisms.
Lesson 9: Selection
Focus Question: How do natural and artificial selection change a population over time?
Students work in groups to carry out an investigation relating to natural selection using beads and different types of habitats. Then, students intentionally hunt for certain colors of beads, modeling the process of artificial selection. Students then consider the selection pressures of both processes and how they lead to evolution.
Lesson 10: Human Manipulation
Focus Question: What are some ways that humans have influenced the inheritance of desired traits in organisms?
Students organize prior knowledge about genetics to consider reasons why humans would want to manipulate an organism's DNA. Then, students observe the different variants of zebra fish in their classroom to construct an explanation to how the different kinds of zebra fish were created. Next, students research different types of genetic modification technologies and compile a list of reliable sources of information.
Lesson 11: Assessment
The unit concludes with a two-part assessment. The first part is a performance assessment, in which students apply the knowledge and skills they have acquired during the unit to research and report on human manipulation of organisms' genetics to produce desirable traits. In the second part, students complete a written assessment covering the performance expectations, disciplinary core ideas, crosscutting concepts, and science and engineering practices covered in this unit.

Note: GloFish® fluorescent fish are licensed under 1 or more United States patents. Reproduction (breeding) of GloFish® is permitted only for educational use by teachers and students in bona fide educational institutions; however, any sale, barter, or trade of the offspring from such reproduction is strictly prohibited.

Note: The Casper Fishprovided are intended for non-commercial, internal research and educational purposes only. The sale, lease, license, or other transfer of the Casper Fishto a for-profit organization, uses of the Casper Fishby any organization, including Recipient, to perform contract research, to screen compound libraries, to produce or manufacture products for general sale, or to conduct research activities that result in any sale, lease, license, or transfer of the Casper Fishto a for-profit organization are strictly prohibited. However, industrially sponsored academic research shall not be considered a use of the Casper Fishfor commercial purposes per se, unless any of the above conditions are met. Customers seeking to use the Casper Fishfor commercial purposes should contact the Technology and Innovation Development Office of Children's Hospital Boston.

Note: Onion bulblets are available October through June.

*Next Generation Science Standards® is a registered trademark of WestEd. Neither WestEd nor the lead states and partners that developed the Next Generation Science Standards were involved in the production of this product, and do not endorse it.

  • This item is only available from Carolina Biological Supply Company.
  • Limited Qty: Flammable Liquid - This product is/contains a limited quantity of a DOT regulated hazardous material. This item will not incur a hazmat fee when shipped by ground. Orders shipping to HI and AK are subject to review and may incur additional shipping charges.

This item includes prepaid coupons for living or perishable materials (all items). Redeem the coupons for delivery of these materials at your convenience at www.carolina.com/livingform, by phone at 800.334.5551, or by fax at 800.222.7112.

Components Qty Included?
Living Materials Order Sheet Set, Genes and Molecular Machines 1 Included
Genes and Molecular Machines Student Guide 16 Included
Genes and Molecular Machines Teacher’s Edition 1 Included
Unit Technology Pack (includes digital access to the Teacher’s Guide and digital student access to the Student Guide) 1 Included
Amazing Bugs® Habitat 1 Included
Aquarium Dip Net 1 Included
Aquarium Kit, Half Moon Bubbling LED, 3 gal 1 Included
Bag, Resealable, Plastic, 4 x 6” 160 Included
Bead, 4-Way, Blue 150 Included
Bead, 4-Way, Green 150 Included
Bead, 4-Way, Purple 150 Included
Bead, 4-Way, Red 300 Included
Bead, 4-Way, Yellow 300 Included
Bead, Blue Pony 2,000 Included
Bead, Green Pony 2,160 Included
Bead, Red Pony 5,000 Included
Bead, Yellow Pony 2,000 Included
Carolina™ Springwater, 1 gal 4 Included
Cheesecloth, 5 yd 5 Included
Container, Deli, 24 oz 100 Included
Container Lid, Plastic, for 16-oz Container 25 Included
Container, Plastic, 16 oz 120 Included
Cotton Wick, 4 x 3/8” 80 Included
Coverslip, Plastic 400 Included
Cup, Culture 80 Included
Cup, Medicine, Plastic, 1 oz 300 Included
Cup Lid, Plastic, Clear, for 4-oz Cup 50 Included
Cup, Plastic, Clear, 4 oz 150 Included
Dice, Standard, 16 mm 36 Included
Dishwashing Liquid, Small Bottle 1 Included
Dough™, Crayola®, Orange, 3 lb 4 Included
Ethanol, 95%, 100 mL 5 Included
Fan, Personal, Battery-Operated (batteries not included) 8 Included
Fertilizer, Osmocote® 14, 1 oz 10 Included
Food, Fish 1 Included
Forceps, Plastic 16 Included
Funnel 16 Included
Hydrochloric Acid, 3.0 M, 120 mL 2 Included
Lady Beetles Diet, 2 oz 1 Included
Lens, Hand 32 Included
Link ’n’ Learn Links 500 Included
Map: Habitat 8 Included
Map: Mitosis Visual 8 Included
Microscope Slides, Student-Grade, Standard 144 Included
Molymod® Advanced miniDNA Set 1 Included
Paper, Filter, 9 cm 300 Included
Pebbles, Rainbow Stone, 5 lb 1 Included
Petri Dish, with Lid 340 Included
Petri Dish, Y Plate, Sterile 20 Included
Photo Card Set, Examination of Slides 4 Included
Photo Card Set, Exploring Cell Types 2 Included
Photo Card Set, Flowers and Pollinators 8 Included
Photo Card, Parent/Offspring 8 Included
Photo Cards, Meiosis 2 Included
Pipe Cleaner, Assorted Colors 900 Included
Pipette, Plastic 500 Included
Plant Dividers Set 80 Included
Pollination Wand 72 Included
Potting Mix, 1-L Bag 35 Included
Salt, 10 g 5 Included
Seed Dispersal Set 5 Included
Seed, Lima Bean, 1/2 lb 1 Included
Seed, Pumpkin 60 Included
Slide Set, Basic Meiosis 3 Included
Slide Set, Exploring Cell Types 1 Included
Slide Set, Reproduction 1 Included
Solution, Lugol, 7.5 mL 8 Included
Solution, Protoslo® Quieting, Lab Grade, 15 mL 8 Included
Spoon, Plastic, and Paintbrush 1 Included
Stick, Wood 90 Included
String, Super Twine, 200-ft Roll 2 Included
Toluidine Blue, 2%, 15-mL Dropper Bottle 4 Included
Toothpick, Round, Box 1 Included
Transparency, Ruler/Fragmenting Tool 20 Included
Tube, Centrifuge, 15 mL 33 Included
Tube, Centrifuge, Non-Sterile 17 Included
Tube, Microcentrifuge, 1.5 mL, PP Natural 50 Included
Microscopes (we recommend item #591182) 16 Needed, Not Included